SCHEMBL307312

SCHEMBL307312

COC(=O)c1cccc([N+](=O)[O-])c1C

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.70
KMT2A Q03164 5/20 0.62
SMN1; SMN2 Q16637 4/20 0.62
MEN1 O00255 4/20 0.62
TDP1 Q9NUW8 1/20 0.60
GLA P06280 1/20 0.60
LMNA P02545 3/20 0.57
L3MBTL1 Q9Y468 3/20 0.56
ALDH1A1 P00352 2/20 0.56
KDM4E B2RXH2 1/20 0.56
CYP2C9 P11712 1/20 0.56
DHODH Q02127 1/20 0.56
MAPK1 P28482 2/20 0.54
GAA P10253 1/20 0.54
MAPT P10636 1/20 0.54
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
HPGD P15428 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29959661 1.00 TSHR (0.70) TSHRKMT2ASMN1; SMN2MEN1TDP1
SCHEMBL27376780 0.92 TSHR (0.60) TSHRKMT2ASMN1; SMN2MEN1TDP1
SCHEMBL529169 0.91 TSHR (0.58) TSHRKMT2ASMN1; SMN2MEN1TDP1
SCHEMBL28018596 0.90 TSHR (0.70) TSHRKMT2ASMN1; SMN2MEN1TDP1
SCHEMBL5509791 0.87 TSHR (0.66) TSHRKMT2ASMN1; SMN2MEN1TDP1
SCHEMBL21073898 0.87 TSHR (0.66) TSHRKMT2ASMN1; SMN2MEN1TDP1
SCHEMBL8032067 0.87 TSHR (0.66) TSHRKMT2ASMN1; SMN2MEN1TDP1
SCHEMBL28775541 0.86 TSHR (0.51) TSHRKMT2ASMN1; SMN2MEN1TDP1
SCHEMBL14933431 0.86 TSHR (0.56) TSHRKMT2ASMN1; SMN2MEN1TDP1
SCHEMBL195311 0.86 ALDH1A1 (0.62) TSHRKMT2ASMN1; SMN2TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 634 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010899-A Continuous flow preparation method of lenalidomide and derivatives thereof 深圳连续制药科技有限公司 2026-05-12 CN claimed
CN-118619834-A Continuous flow nitration synthesis method of methyl o-methylbenzoate in microchannel reactor 南京理工大学 2024-09-10 CN claimed
EP-4402478-A1 METHOD FOR DETERMINING AT LEAST ONE ANALYTE OF INTEREST F. Hoffmann-La Roche AG (CH) 2024-07-24 EP claimed
US-20240219401-A1 METHOD FOR DETERMINING AT LEAST ONE ANALYTE OF INTEREST ROCHE DIAGNOSTICS OPERATIONS, INC. 2024-07-04 US claimed
CN-117957447-A Method for determining at least one analyte of interest 豪夫迈·罗氏有限公司 2024-04-30 CN claimed
CN-114076801-B Detection method of related substances in lenalidomide 上海博志研新药物研究有限公司 2024-04-02 CN claimed
CN-115557842-B Preparation method of lenalidomide intermediate 哈尔滨工业大学(深圳) 2024-01-09 CN claimed
WO-2023041571-A1 METHOD FOR DETERMINING AT LEAST ONE ANALYTE OF INTEREST F. HOFFMANN-LA ROCHE AG (CH) 2023-03-23 WO claimed
CN-115557842-A Preparation method of lenalidomide intermediate 哈尔滨工业大学(深圳) 2023-01-03 CN claimed
WO-2022222272-A1 SYNTHESIS PROCESS OF 2-METHYL-3-METHOXYBENZOIC ACID 江苏永安化工有限公司 2022-10-27 WO claimed
EP-2545043-B1 ANHYDROUS LENALIDOMIDE FORM-I NATCO PHARMA LTD (IN) 2019-04-24 EP claimed
CN-109384667-A A kind of synthesis technology of 2- methyl -3- methoxy benzoyl chloride 江苏永安化工有限公司 2019-02-26 CN claimed
US-20160018361-A1 SYSTEM AND METHODS FOR IONIZING COMPOUNDS USING MATRIX-ASSISTANCE FOR MASS SPECTROMETRY AND ION MOBILITY SPECTROMETRY MSTM, LLC 2016-01-21 US claimed
US-9105458-B2 System and methods for ionizing compounds using matrix-assistance for mass spectrometry and ion mobility spectrometry MSTM, LLC 2015-08-11 US claimed
WO-2015057043-A1 A PROCESS FOR THE PREPARATION OF LENALIDOMIDE LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) 2015-04-23 WO claimed
CN-104311536-A Method for preparing lenalidomide SHANGHAI INST TECHNOLOGY 2015-01-28 CN claimed
US-20130306856-A1 System and Methods for Ionizing Compounds using Matrix-assistance for Mass Spectometry and Ion Mobility Spectometry MSTM, LLC 2013-11-21 US claimed
CN-101959856-A Preparation of lenalidomide REDDYS LAB LTD 2011-01-26 CN claimed
CN-101665484-A Method for preparing lenalidomide SHANGHAI HAOYUAN CHEMEXPRESS B 2010-03-10 CN claimed
CN-101245045-A Process for synthesizing indole-4-methanal UNIV SOUTHEAST (CN) 2008-08-20 CN claimed