Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719902 | 0.89 | TSHR (0.53) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL6803090 | 0.87 | TSHR (0.50) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL307312 | 0.86 | TSHR (0.70) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL29959661 | 0.86 | TSHR (0.70) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL195311 | 0.86 | ALDH1A1 (0.62) | TSHRSMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL50994 | 0.85 | TSHR (0.54) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL391265 | 0.85 | GPR35 (0.58) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL7369896 | 0.85 | TSHR (0.54) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL31258847 | 0.85 | GPR35 (0.58) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL6690612 | 0.84 | ALDH1A1 (0.53) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9337430-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2016-05-10 | — | — | US | disclosed |
| US-9337430-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2016-05-10 | — | — | US | disclosed |
| EP-2773721-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2015-11-25 | — | — | EP | disclosed |
| US-20140249308-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2014-09-04 | — | — | US | disclosed |
| US-20140249308-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2014-09-04 | — | — | US | disclosed |
| WO-2013064206-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |