SCHEMBL30731531

SCHEMBL30731531

CNc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1C

nearest known ligand 0.64

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ADORA3 P0DMS8 5/20 0.61
▸ ADORA1 P30542 5/20 0.61
▸ HPGD P15428 1/20 0.57
▸ ADORA2A P29274 4/20 0.56
▸ ADORA2B P29275 3/20 0.56
▸ LMNA P02545 1/20 0.55
▸ TP53 P04637 1/20 0.55
▸ CYP2C19 P33261 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31685564 0.89 MEN1 (0.51) ADORA3ADORA1HPGDADORA2AADORA2B
SCHEMBL20548039 0.87 ADORA2A (0.53) ADORA3ADORA1HPGDADORA2AADORA2B
SCHEMBL6365742 0.86 HPGD (0.52) ADORA3ADORA1HPGDADORA2AADORA2B
SCHEMBL31685735 0.86 ADORA1 (0.52) ADORA3ADORA1ADORA2AADORA2B
SCHEMBL31685449 0.85 IMPDH2 (0.62) ADORA1
SCHEMBL62505 0.85 CYP2C19 (0.62) ADORA3ADORA1HPGDADORA2AADORA2B
SCHEMBL18844803 0.85 CYP2C19 (0.62) ADORA3ADORA1HPGDADORA2AADORA2B
SCHEMBL14931005 0.85 CYP2C19 (0.62) ADORA3ADORA1HPGDADORA2AADORA2B
SCHEMBL343478 0.85 CYP2C19 (0.62) ADORA3ADORA1HPGDADORA2AADORA2B
SCHEMBL18512921 0.85 CYP2C19 (0.62) ADORA3ADORA1HPGDADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 — — US disclosed
US-20240011031-A1 COMPOSITIONS COMPRISING A NUCLEASE AND USES THEREOF Arbor Biotechnologies, Inc. (US) 2024-01-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 ADORA3 655/4885ADORA1 935/4885HPGD 4461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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