SCHEMBL30733468

SCHEMBL30733468

CCCCCCCCCCCCCCCCCCOCCOC1C(OP(OCCC#N)N(C(C)C)C(C)C)[C@H](n2ccc(=O)[nH]c2=O)O[C@@H]1COC(c1ccccc1)(c1ccc(OC)cc1)c1ccc(OC)cc1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.33
P2RY14 Q15391 2/20 0.33
P2RY2 P41231 1/20 0.33
P2RY4 P51582 1/20 0.33
P2RY12 Q9H244 1/20 0.31
DUT P33316 1/20 0.31
PLA2G2A P14555 2/20 0.30
PLA2G10 O15496 1/20 0.30
PLA2G1B P04054 1/20 0.30
PLA2G5 P39877 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30733449 1.00 TYMP (0.33) TYMPP2RY14P2RY2P2RY4P2RY12
SCHEMBL31744952 0.98 TYMP (0.33) TYMPP2RY14P2RY2P2RY4P2RY12
SCHEMBL30733461 0.98 TYMP (0.33) TYMPP2RY14P2RY2P2RY4P2RY12
SCHEMBL31744991 0.97 TYMP (0.32) TYMPP2RY14P2RY2P2RY4
SCHEMBL31744944 0.94 TYMP (0.32) TYMPP2RY14P2RY2P2RY4
SCHEMBL6933190 0.94 TYMP (0.35) TYMPP2RY14P2RY2P2RY4P2RY12
SCHEMBL6932021 0.94 TYMP (0.35) TYMPP2RY14P2RY2P2RY4P2RY12
SCHEMBL6933255 0.91 TYMP (0.36) TYMPP2RY14P2RY2P2RY4P2RY12
SCHEMBL31744920 0.90 TYMP (0.33) TYMPP2RY14P2RY2P2RY4P2RY12
SCHEMBL3927922 0.90 TYMP (0.37) TYMPP2RY14P2RY2P2RY4P2RY12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382324-A1 MONOMERS AND METHODS FOR SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC. (US) 2025-12-18 US disclosed
EP-4547852-A2 MONOMERS AND METHODS FOR SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES Alnylam Pharmaceuticals, Inc. (US) 2025-05-07 EP disclosed
WO-2024006953-A2 MONOMERS AND METHODS FOR SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC. (US) 2024-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382324-A1 MONOMERS AND METHODS FOR SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES POLM, PCNA, POLRMT TYMP 83/4885P2RY14 3785/4885P2RY2 4545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.