Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.57 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786562 | 1.00 | ACHE (0.57) | ACHETLR2EPHX1 | |
| SCHEMBL30786561 | 1.00 | ACHE (0.57) | ACHETLR2EPHX1 | |
| SCHEMBL4622478 | 0.98 | ACHE (0.59) | ACHEEPHX1 | |
| SCHEMBL30080644 | 0.91 | ACHE (0.58) | ACHETLR2EPHX1 | |
| SCHEMBL17841292 | 0.90 | ACHE (0.57) | ACHEEPHX1 | |
| SCHEMBL30080594 | 0.89 | ACHE (0.61) | ACHETLR2EPHX1 | |
| SCHEMBL7380504 | 0.87 | ACHE (0.50) | ACHE | |
| SCHEMBL4761605 | 0.86 | ACHE (0.60) | ACHE | |
| SCHEMBL29612809 | 0.85 | ACHE (0.67) | ACHE | |
| SCHEMBL7494523 | 0.85 | ACHE (0.67) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519273-A1 | KRAS G12D PROTEOLYSIS TARGETING CHIMERAS | Paq Therapeutics Inc. (US) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023215906-A1 | KRAS G12D PROTEOLYSIS TARGETING CHIMERAS | HANGZHOU JIJING PHARMACEUTICALTECHNOLOGY LIMITED (CN) | 2023-11-09 | — | — | WO | disclosed |