Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786562 | 0.87 | ACHE (0.57) | ACHE | |
| SCHEMBL30786561 | 0.87 | ACHE (0.57) | ACHE | |
| SCHEMBL30733875 | 0.87 | ACHE (0.57) | ACHE | |
| SCHEMBL4622478 | 0.85 | ACHE (0.59) | ACHE | |
| SCHEMBL20706221 | 0.85 | TSHR (0.47) | ACHETSHRRECQLFAAH | |
| SCHEMBL7380506 | 0.83 | ACHE (0.47) | ACHETSHRRECQLFAAH | |
| SCHEMBL8214500 | 0.82 | GLP1R (0.46) | ACHETSHRRECQLFAAH | |
| SCHEMBL17227467 | 0.82 | FAAH (0.55) | TSHRRECQLFAAH | |
| SCHEMBL21297376 | 0.82 | GLP1R (0.46) | ACHETSHRRECQLFAAH | |
| SCHEMBL24838579 | 0.82 | TSHR (0.39) | ACHETSHRRECQLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002070521-A1 | NOVEL METALLOPROTEINASE INHIBITOR DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2002-09-12 | — | — | WO | disclosed |