Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP4 | P49662 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19586107 | 1.00 | L3MBTL1 (0.51) | L3MBTL1MAPTCYP1A2CNR2HTT | |
| SCHEMBL31745993 | 0.88 | L3MBTL1 (0.62) | L3MBTL1MAPTCYP1A2CNR2MEN1 | |
| SCHEMBL13106155 | 0.88 | L3MBTL1 (0.62) | L3MBTL1MAPTCYP1A2CNR2MEN1 | |
| SCHEMBL3380500 | 0.83 | L3MBTL1 (0.52) | L3MBTL1MAPTCYP1A2CNR2HTT | |
| SCHEMBL30955734 | 0.81 | L3MBTL1 (0.51) | L3MBTL1MAPTCNR2HTTTDP1 | |
| SCHEMBL26621652 | 0.81 | L3MBTL1 (0.51) | L3MBTL1MAPTCYP1A2CNR2HTT | |
| SCHEMBL14909376 | 0.81 | L3MBTL1 (0.51) | L3MBTL1MAPTCYP1A2CNR2HTT | |
| SCHEMBL13106375 | 0.79 | L3MBTL1 (0.49) | L3MBTL1MAPTCYP1A2CNR2HTT | |
| SCHEMBL4660529 | 0.78 | ELANE (0.44) | L3MBTL1MAPTCYP1A2TDP1CYP3A4 | |
| SCHEMBL2851292 | 0.78 | L3MBTL1 (0.51) | L3MBTL1MAPTCYP1A2CNR2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096706-A1 | MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-05-08 | — | — | WO | disclosed |
| EP-4519259-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023215482-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-11-09 | — | — | WO | disclosed |