SCHEMBL31745993

SCHEMBL31745993

Cn1nc(I)c2cc([N+](=O)[O-])ccc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.62
CNR2 P34972 4/20 0.52
MAPT P10636 7/20 0.51
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
LMNA P02545 2/20 0.44
CNR1 P21554 1/20 0.44
ACHE P22303 1/20 0.44
CYP1A2 P05177 1/20 0.44
POLB P06746 1/20 0.43
ATM Q13315 1/20 0.43
F2 P00734 1/20 0.41
PLAU P00749 1/20 0.41
KLKB1 P03952 1/20 0.41
ELANE P08246 1/20 0.41
CTRB1 P17538 1/20 0.41
F2R P25116 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
F2RL3 Q96RI0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13106155 1.00 L3MBTL1 (0.62) L3MBTL1CNR2MAPTMEN1KMT2A
SCHEMBL30734745 0.88 L3MBTL1 (0.51) L3MBTL1CNR2MAPTMEN1KMT2A
SCHEMBL19586107 0.88 L3MBTL1 (0.51) L3MBTL1CNR2MAPTMEN1KMT2A
SCHEMBL29094193 0.83 L3MBTL1 (0.63) L3MBTL1CNR2MAPTMEN1KMT2A
SCHEMBL3532423 0.83 L3MBTL1 (0.46) L3MBTL1CNR2MAPTMEN1KMT2A
SCHEMBL29741986 0.83 L3MBTL1 (0.63) L3MBTL1CNR2MAPTMEN1KMT2A
SCHEMBL12193567 0.83 L3MBTL1 (0.63) L3MBTL1CNR2MAPTMEN1KMT2A
SCHEMBL30628634 0.81 L3MBTL1 (0.62) L3MBTL1CNR2MAPTMEN1KMT2A
SCHEMBL14908618 0.81 L3MBTL1 (0.62) L3MBTL1CNR2MAPTMEN1KMT2A
Ammonia Solution, Strong SCHEMBL27978075 0.81 L3MBTL1 (0.62) L3MBTL1CNR2MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382292-A1 COMPOUNDS FOR TREATING LIGHT CHAIN AMYLOIDOSIS PROTEGO BIOPHARMA INC (US) 2025-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382292-A1 COMPOUNDS FOR TREATING LIGHT CHAIN AMYLOIDOSIS TTR, CRYAA, BCL6 L3MBTL1 2798/4885CNR2 4403/4885MAPT 25/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.