Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26637184 | 1.00 | GPR119 (0.50) | GPR119KDM4EPKMFAAH | |
| SCHEMBL30735309 | 0.85 | PRMT5 (0.45) | GPR119KDM4EPKM | |
| SCHEMBL26636928 | 0.85 | PRMT5 (0.45) | GPR119KDM4EPKM | |
| SCHEMBL30663176 | 0.84 | GPR119 (0.57) | GPR119KDM4EPKMFAAH | |
| SCHEMBL26619651 | 0.84 | GPR119 (0.57) | GPR119KDM4EPKMFAAH | |
| SCHEMBL26619523 | 0.83 | GPR119 (0.56) | GPR119KDM4EPKMFAAH | |
| SCHEMBL30657348 | 0.83 | GPR119 (0.56) | GPR119KDM4EPKMFAAH | |
| SCHEMBL30735441 | 0.81 | KDM1A (0.47) | GPR119KDM4EPKMFAAH | |
| SCHEMBL26636291 | 0.81 | KDM1A (0.47) | GPR119KDM4EPKMFAAH | |
| SCHEMBL26636285 | 0.81 | KDM1A (0.47) | GPR119KDM4EPKMFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519259-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023215482-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-11-09 | — | — | WO | disclosed |