Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123978 | 1.00 | NPSR1 (0.43) | NPSR1TDP1HTR6DRD2HTR2A | |
| SCHEMBL30735530 | 0.87 | TDP1 (0.52) | TDP1HTR6DRD2HTR2AHTR7 | |
| SCHEMBL29123942 | 0.86 | LIMK1 (0.53) | TDP1DRD2HTR2AHTR1AHDAC1 | |
| SCHEMBL30735676 | 0.86 | LIMK1 (0.53) | TDP1DRD2HTR2AHTR1AHDAC1 | |
| SCHEMBL29123959 | 0.86 | HTR1A (0.46) | TDP1HTR6DRD2HTR2AHTR7 | |
| SCHEMBL30735551 | 0.86 | HTR1A (0.46) | TDP1HTR6DRD2HTR2AHTR7 | |
| SCHEMBL30735479 | 0.81 | TDP1 (0.53) | TDP1HTR6DRD2HTR2AHTR7 | |
| SCHEMBL30735480 | 0.81 | TDP1 (0.53) | TDP1HTR6DRD2HTR2AHTR7 | |
| SCHEMBL29123960 | 0.77 | MEN1 (0.43) | ALDH1A1KMT2A | |
| SCHEMBL30735687 | 0.76 | TDP1 (0.51) | TDP1HTR6DRD2HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229257-A | Meta-sulfamoyl benzamide compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2023-12-15 | — | — | CN | disclosed |