Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 3/20 | 0.53 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123942 | 1.00 | LIMK1 (0.53) | LIMK1LIMK2AKR1C3HDAC6HDAC1 | |
| SCHEMBL30735530 | 0.91 | TDP1 (0.52) | AKR1C3KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL30735551 | 0.90 | HTR1A (0.46) | LIMK1LIMK2HDAC6HDAC1TDP1 | |
| SCHEMBL29123959 | 0.90 | HTR1A (0.46) | LIMK1LIMK2HDAC6HDAC1TDP1 | |
| SCHEMBL30735485 | 0.86 | NPSR1 (0.43) | LIMK1AKR1C3HDAC6HDAC1KMT2A | |
| SCHEMBL29123978 | 0.86 | NPSR1 (0.43) | LIMK1AKR1C3HDAC6HDAC1KMT2A | |
| SCHEMBL30735479 | 0.85 | TDP1 (0.53) | AKR1C3KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL30735480 | 0.85 | TDP1 (0.53) | AKR1C3TDP1ALDH1A1LMNAHTR1A | |
| SCHEMBL30735687 | 0.80 | TDP1 (0.51) | AKR1C3TDP1ALDH1A1LMNAPKM | |
| SCHEMBL29123951 | 0.78 | CYP2C19 (0.68) | AKR1C3KMT2ATDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229257-A | Meta-sulfamoyl benzamide compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2023-12-15 | — | — | CN | disclosed |