Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.50 |
| ▸ | CCR8 | P51685 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19284604 | 1.00 | GPR119 (0.50) | GPR119CCR8STSBRD4BACE1 | |
| SCHEMBL20914758 | 0.96 | GPR119 (0.49) | GPR119CCR8STSBRD4BACE1 | |
| SCHEMBL19297027 | 0.92 | HTR6 (0.52) | GPR119CCR8STSBRD4KDM4E | |
| SCHEMBL19284581 | 0.85 | CCR8 (0.49) | GPR119CCR8STSBRD4CHRM2 | |
| SCHEMBL19284629 | 0.84 | CCR8 (0.48) | GPR119CCR8STSBRD4KDM4E | |
| SCHEMBL4422025 | 0.80 | GPR119 (0.47) | GPR119 | |
| SCHEMBL19284712 | 0.80 | GPR119 (0.52) | GPR119BACE1CHRM2CHRM4CHRM1 | |
| SCHEMBL19284736 | 0.79 | HTR6 (0.56) | GPR119CCR8STS | |
| SCHEMBL19284731 | 0.79 | CCR8 (0.54) | GPR119CCR8BRD4BACE1CHRM2 | |
| SCHEMBL19284642 | 0.79 | PDE4B (0.53) | GPR119BACE1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11891369-B2 | Compounds for binding proprotein convertase subtilisin/kexin type 9 | SRX CARDIO, LLC (US) | 2024-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891369-B2 | Compounds for binding proprotein convertase subtilisin/kexin type 9 | PCSK9, PCSK6, PCSK7 | GPR119 405/4885CCR8 2271/4885STS 2824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.