Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 10/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19284659 | 1.00 | HTR6 (0.54) | HTR6HTR2CADRB2CYP1A2CYP2A6 | |
| Hydrochloric Acid SCHEMBL19284709 | 0.98 | HTR2C (0.53) | HTR6HTR2CADRB2CYP1A2CYP2A6 | |
| SCHEMBL28112604 | 0.87 | CYP1A2 (0.56) | HTR6HTR2CCYP1A2CYP2A6HTR1A | |
| SCHEMBL19284708 | 0.81 | HTR6 (0.56) | HTR6HTR2CADRB2HTR1ASLC6A2 | |
| SCHEMBL30735827 | 0.81 | HTR6 (0.56) | HTR6HTR2CADRB2HTR1ASLC6A2 | |
| Hydrochloric Acid SCHEMBL19284610 | 0.80 | HTR2C (0.56) | HTR6HTR2CADRB2HTR1ASLC6A2 | |
| SCHEMBL30735853 | 0.79 | RPS6KA3 (0.42) | HTR6HTR2CADRB2HTR1ASLC6A2 | |
| SCHEMBL19297189 | 0.79 | RPS6KA3 (0.42) | HTR6HTR2CADRB2HTR1ASLC6A2 | |
| SCHEMBL19297111 | 0.79 | RPS6KA3 (0.42) | HTR6HTR2CADRB2HTR1ASLC6A2 | |
| SCHEMBL30735800 | 0.79 | RPS6KA3 (0.42) | HTR6HTR2CADRB2HTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11891369-B2 | Compounds for binding proprotein convertase subtilisin/kexin type 9 | SRX CARDIO, LLC (US) | 2024-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891369-B2 | Compounds for binding proprotein convertase subtilisin/kexin type 9 | PCSK9, PCSK6, PCSK7 | HTR6 2874/4885HTR2C 3255/4885ADRB2 3352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.