Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11387812 | 1.00 | ATM (0.48) | ATMSIGMAR1CNR1CNR2ADRA1D | |
| SCHEMBL7207568 | 0.83 | ATM (0.43) | ATMSIGMAR1ADRA1DADRA1AADRA1B | |
| SCHEMBL2320079 | 0.83 | SIGMAR1 (0.46) | ATMSIGMAR1ADRA1DADRA1AADRA1B | |
| SCHEMBL14666732 | 0.79 | HTR2C (0.50) | ATMCNR1CNR2MAOB | |
| SCHEMBL7466569 | 0.79 | KDM4E (0.60) | ATMCNR1CNR2MAOBMAPT | |
| SCHEMBL3029269 | 0.78 | ALDH1A1 (0.66) | MAOBMAPT | |
| SCHEMBL3322611 | 0.78 | MAPT (0.43) | ATMCNR1CNR2MAOBMAPT | |
| SCHEMBL20587128 | 0.78 | MAPT (0.47) | ATMCNR1CNR2MAOBMAPT | |
| SCHEMBL30953660 | 0.78 | HASPIN (0.38) | CNR1CNR2 | |
| SCHEMBL2319623 | 0.78 | MAOB (0.47) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240317728-A1 | COMPOUNDS AND METHODS OF PREPARING COMPOUNDS S1P1 MODULATORS | TREVENA, INC. | 2024-09-26 | — | — | US | disclosed |
| US-11884655-B2 | Compounds and methods of preparing compounds S1P1 modulators | TREVENA, INC. (US) | 2024-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240317728-A1 | COMPOUNDS AND METHODS OF PREPARING COMPOUNDS S1P1 MODULATORS | S1PR1, S1PR2, S1PR5 | ATM 3694/4885SIGMAR1 736/4885CNR1 29/4885 |
| US-11884655-B2 | Compounds and methods of preparing compounds S1P1 modulators | S1PR1, S1PR2, S1PR5 | ATM 3694/4885SIGMAR1 736/4885CNR1 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.