SCHEMBL30736100

SCHEMBL30736100

CNS(=O)(=O)c1cnc(CC#N)cn1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3680387 0.74 MEN1 (0.54) MEN1MAPTKMT2A
SCHEMBL426787 0.68 EDNRA (0.35)
SCHEMBL30736092 0.67 MEN1 (0.44) MEN1MAPTKMT2A
SCHEMBL25826358 0.67 MEN1 (0.44) MEN1MAPTKMT2A
SCHEMBL31360488 0.66 ALDH1A1 (0.31) MAPT
SCHEMBL30736216 0.65 SIRT6 (0.43) MEN1MAPTKMT2A
SCHEMBL18343470 0.65 MAPK1 (0.44) MEN1MAPTKMT2A
SCHEMBL25231594 0.64 MEN1 (0.44) MEN1MAPTKMT2A
SCHEMBL2644333 0.64 MEN1 (0.44) MEN1MAPTKMT2A
SCHEMBL23171261 0.64 MEN1 (0.44) MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382297-A1 INHIBITORS OF FGFR2 AND FGFR3 AND USES THEREOF INSILICO MEDICINE IP LTD (HK) 2025-12-18 US disclosed
EP-4547669-A1 INHIBITORS OF FGFR2 AND FGFR3 AND USES THEREOF Insilico Medicine IP Limited (HK) 2025-05-07 EP disclosed
CN-119451964-A FGFR2 and FGFR3 inhibitors and uses thereof 英矽智能科技知识产权有限公司 2025-02-14 CN disclosed
WO-2024002157-A1 INHIBITORS OF FGFR2 AND FGFR3 AND USES THEREOF INSILICO MEDICINE IP LIMITED (CN) 2024-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382297-A1 INHIBITORS OF FGFR2 AND FGFR3 AND USES THEREOF FGFR3, FGFR2, FGFR1 MEN1 1922/4885MAPT 2467/4885KMT2A 2220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.