SCHEMBL30736670

SCHEMBL30736670

COC(=O)c1cc(C2CCN(C(=O)OC(C)(C)C)CC2)ccc1C(F)(F)F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.49
NAMPT P43490 1/20 0.49
PDE4B Q07343 1/20 0.48
P2RY14 Q15391 1/20 0.47
KDM4E B2RXH2 1/20 0.46
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.46
RBP4 P02753 2/20 0.45
EED O75530 1/20 0.45
RBBP4 Q09028 1/20 0.45
SUZ12 Q15022 1/20 0.45
EZH2 Q15910 1/20 0.45
AEBP2 Q6ZN18 1/20 0.45
DDB1 Q16531 1/20 0.45
CRBN Q96SW2 1/20 0.45
STS P08842 1/20 0.44
ALDH1A1 P00352 1/20 0.44
JAK3 P52333 2/20 0.43
PTK2 Q05397 2/20 0.43
SFRP1 Q8N474 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30736663 0.91 EPHX2 (0.49) EPHX2NAMPTPDE4BP2RY14KDM4E
SCHEMBL3161217 0.87 NAMPT (0.51) NAMPTPDE4BKDM4EMAPTTHRB
SCHEMBL29181014 0.85 NAMPT (0.52) NAMPTPDE4BKDM4EMAPTTHRB
SCHEMBL15380057 0.84 NAMPT (0.51) NAMPTPDE4BKDM4EMAPTTHRB
SCHEMBL19097504 0.83 NAMPT (0.52) NAMPTPDE4BKDM4EMAPTTHRB
SCHEMBL30736753 0.83 NAMPT (0.52) NAMPTPDE4BKDM4EMAPTTHRB
SCHEMBL20570524 0.83 GPR119 (0.54) EPHX2PDE4BEEDRBBP4SUZ12
SCHEMBL16991970 0.82 PDE4B (0.60) NAMPTPDE4BKDM4EMAPTTHRB
SCHEMBL19703142 0.82 GPR119 (0.55) EPHX2NAMPTPDE4BP2RY14KDM4E
SCHEMBL19103520 0.82 NAMPT (0.50) EPHX2NAMPTPDE4BP2RY14KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4561575-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME Cedilla Therapeutics, Inc. (US) 2025-06-04 EP disclosed