SCHEMBL30736968

SCHEMBL30736968

CC(C)(C)OC(=O)NCCN1CC(N2CCN(CC(=O)O)CC2)C1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CACNA1H O95180 1/20 0.52
▸ DRD2 P14416 8/20 0.45
▸ MEN1 O00255 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ SIGMAR1 Q99720 3/20 0.40
▸ EPHX1 P07099 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ SUCNR1 Q9BXA5 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ GFER P55789 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30736943 0.89 CACNA1H (0.51) CACNA1HDRD2MEN1GAAKMT2A
SCHEMBL30737230 0.87 CACNA1H (0.60) CACNA1HDRD2MEN1GAAKMT2A
SCHEMBL15686293 0.86 CACNA1H (0.48) CACNA1HDRD2MEN1GAAKMT2A
SCHEMBL30736833 0.80 CACNA1H (0.56) CACNA1HDRD2MEN1GAAKMT2A
SCHEMBL30737029 0.80 CACNA1H (0.54) CACNA1HDRD2SIGMAR1EPHX1
SCHEMBL31301242 0.78 DRD2 (0.63) CACNA1HDRD2MEN1GAAKMT2A
SCHEMBL25304781 0.77 CACNA1H (0.47) CACNA1HDRD2MEN1GAAKMT2A
SCHEMBL31465614 0.77 DRD2 (0.58) CACNA1HDRD2MEN1GAAKMT2A
SCHEMBL31110037 0.76 DRD2 (0.55) CACNA1HDRD2MEN1GAAKMT2A
SCHEMBL31421588 0.76 CACNA1H (0.50) CACNA1HDRD2MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4580405-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL Oerth Bio LLC (US) 2025-07-09 — — EP disclosed
WO-2024050016-A9 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2025-04-03 — — WO disclosed
WO-2025049555-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2025-03-06 — — WO disclosed
WO-2024050016-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2024-03-07 — — WO disclosed
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