Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18604600 | 0.93 | DRD2 (0.58) | DRD2TDP1CACNA1HSIGMAR1MAOA | |
| SCHEMBL31637609 | 0.92 | DRD2 (0.58) | DRD2TDP1CACNA1HSIGMAR1MAOA | |
| SCHEMBL3524057 | 0.90 | DRD2 (0.66) | DRD2TDP1CACNA1HSIGMAR1MAOA | |
| SCHEMBL31465614 | 0.88 | DRD2 (0.58) | DRD2TDP1CACNA1HSIGMAR1MAOA | |
| SCHEMBL18604593 | 0.88 | DRD2 (0.57) | DRD2TDP1CACNA1HSIGMAR1MEN1 | |
| SCHEMBL21465932 | 0.87 | DRD2 (0.53) | DRD2TDP1CACNA1HSIGMAR1MAOA | |
| SCHEMBL29263630 | 0.86 | DRD2 (0.62) | DRD2TDP1SIGMAR1MAOAMAOB | |
| SCHEMBL4572542 | 0.85 | DRD2 (0.60) | DRD2TDP1SIGMAR1MAOAMAOB | |
| SCHEMBL8254760 | 0.84 | DRD2 (0.64) | DRD2TDP1CACNA1HSIGMAR1MEN1 | |
| SCHEMBL5856688 | 0.84 | DRD2 (0.59) | DRD2TDP1CACNA1HSIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4580405-A1 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | Oerth Bio LLC (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024050016-A9 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | OERTH BIO LLC (US) | 2025-04-03 | — | — | WO | disclosed |
| WO-2025049555-A1 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | OERTH BIO LLC (US) | 2025-03-06 | — | — | WO | disclosed |
| WO-2024050016-A1 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | OERTH BIO LLC (US) | 2024-03-07 | — | — | WO | disclosed |