Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GCK | P35557 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GRN | P28799 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31646216 | 0.89 | MAPT (0.50) | MAPTKMT2ACHEK1CHEK2LMNA | |
| SCHEMBL30737388 | 0.89 | CHEK2 (0.45) | MAPTKMT2ACHEK1CHEK2LMNA | |
| SCHEMBL4254797 | 0.85 | KDM4E (0.61) | MAPTGCKKMT2ALMNAMAPK1 | |
| SCHEMBL19405962 | 0.81 | NR4A2 (0.62) | GCKKMT2AMEN1 | |
| SCHEMBL30374769 | 0.81 | MAPT (0.68) | MAPTHCAR3L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL841190 | 0.81 | MAPT (0.68) | MAPTHCAR3L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL30803809 | 0.80 | MAPT (0.51) | MAPTKMT2ALMNAL3MBTL1MEN1 | |
| SCHEMBL31646549 | 0.79 | SORT1 (0.60) | GCKCHEK1CHEK2GRNSORT1 | |
| SCHEMBL31646784 | 0.79 | GRN (0.45) | MAPTKMT2ALMNAMAPK1L3MBTL1 | |
| SCHEMBL30737460 | 0.79 | F10 (0.56) | MAPTKMT2AMAPK1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025133234-A1 | SORTILIN BINDERS AND BIFUNCTIONAL COMPOUNDS THEREOF | DRAUPNIR BIO APS (DK) | 2025-06-26 | — | — | WO | disclosed |
| EP-4543858-A1 | BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES | Draupnir Bio ApS (DK) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247754-A1 | BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES | DRAUPNIR BIO APS (DK) | 2023-12-28 | — | — | WO | disclosed |