SCHEMBL30737460

SCHEMBL30737460

CNC(=O)c1cccc(Oc2ccc(C(=O)O)cn2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F10 P00742 3/20 0.56
F2 P00734 2/20 0.56
MEN1 O00255 1/20 0.53
CASP3 P42574 1/20 0.53
KMT2A Q03164 1/20 0.53
SENP8 Q96LD8 1/20 0.53
SENP7 Q9BQF6 1/20 0.53
SENP6 Q9GZR1 1/20 0.53
OPRM1 P35372 1/20 0.51
OPRD1 P41143 1/20 0.51
GAA P10253 2/20 0.49
MAPT P10636 2/20 0.49
MAPK1 P28482 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
MRGPRX4 Q96LA9 1/20 0.49
HRH3 Q9Y5N1 2/20 0.47
LOX P28300 2/20 0.47
LOXL2 Q9Y4K0 2/20 0.47
AKR1C3 P42330 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30737317 0.89 F10 (0.52) F10F2MEN1CASP3KMT2A
SCHEMBL30737060 0.89 L3MBTL1 (0.52) F10F2MEN1CASP3KMT2A
SCHEMBL13366029 0.85 F10 (0.53) F10F2MEN1CASP3KMT2A
SCHEMBL6120802 0.84 OPRM1 (0.67) OPRM1OPRD1HRH3GRNSORT1
SCHEMBL31646829 0.83 L3MBTL1 (0.54) F10F2MEN1CASP3KMT2A
SCHEMBL30803809 0.81 MAPT (0.51) F10F2MEN1KMT2AMAPT
SCHEMBL4254797 0.81 KDM4E (0.61) MEN1CASP3KMT2ASENP8SENP7
SCHEMBL11304260 0.80 F10 (0.56) F10F2MEN1CASP3KMT2A
SCHEMBL30737207 0.80 GRN (0.45) F10F2MEN1CASP3KMT2A
SCHEMBL30737068 0.80 GRN (0.45) F10F2MEN1CASP3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed