SCHEMBL30737313

SCHEMBL30737313

CNC(=O)c1cccc(Oc2ccc(C(=O)N[C@@H](CCC(C)(C)C)C(=O)O)cn2)c1

nearest known ligand 0.79

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SORT1 Q99523 4/20 0.79
GRN P28799 3/20 0.79
GPR132 Q9UNW8 10/20 0.47
CTSA P10619 2/20 0.44
OPRM1 P35372 1/20 0.44
OPRD1 P41143 1/20 0.44
MEN1 O00255 1/20 0.43
CASP3 P42574 1/20 0.43
KMT2A Q03164 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
F2 P00734 1/20 0.43
F10 P00742 1/20 0.43
CMKLR2 P46091 1/20 0.42
CMKLR1 Q99788 1/20 0.42
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25273962 0.88 SORT1 (1.00) SORT1GRNCTSAOPRM1OPRD1
SCHEMBL24283502 0.88 SORT1 (1.00) SORT1GRNCTSAOPRM1OPRD1
SCHEMBL30737318 0.86 SORT1 (0.77) SORT1GRNGPR132CTSAOPRM1
SCHEMBL30736918 0.85 SORT1 (0.69) SORT1GRNCTSAOPRM1OPRD1
SCHEMBL30737105 0.85 SORT1 (0.69) SORT1GRNCTSAOPRM1OPRD1
SCHEMBL30737175 0.85 SORT1 (0.64) SORT1GRNGPR132CTSAOPRM1
SCHEMBL30737250 0.84 SORT1 (0.73) SORT1GRNGPR132CTSAOPRM1
SCHEMBL30737037 0.83 SORT1 (0.72) SORT1GRNGPR132CTSAOPRM1
SCHEMBL30737138 0.82 SORT1 (0.65) SORT1GRNCTSAOPRM1OPRD1
SCHEMBL30737387 0.82 SORT1 (0.65) SORT1GRNCTSAOPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed