Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 11/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MLYCD | O95822 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30737599 | 0.98 | HPGD (0.61) | HPGDALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL30737654 | 0.95 | HPGD (0.56) | HPGDALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL30737764 | 0.82 | ACACB (0.47) | HPGDALDH1A1TSHRCA12CA1 | |
| SCHEMBL15448626 | 0.81 | HDAC1 (0.52) | HPGDALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL27479149 | 0.80 | HPGD (1.00) | HPGDALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL7132525 | 0.80 | HPGD (1.00) | HPGDALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL10721733 | 0.78 | HPGD (0.95) | HPGDALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL395103 | 0.78 | GSK3B (0.48) | HPGDALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL30737566 | 0.78 | CECR2 (0.41) | HPGDALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL3633068 | 0.78 | HPGD (0.71) | HPGDALDH1A1MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510505-A | Pyrimidopyrazoles derivatives and their use in medicine | 中国药科大学 | 2024-02-06 | — | — | CN | disclosed |