Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436187 | 1.00 | SENP1 (0.37) | SENP1CASP1CHEK1DAPK3PRKD3 | |
| SCHEMBL436186 | 1.00 | SENP1 (0.37) | SENP1CASP1CHEK1DAPK3PRKD3 | |
| SCHEMBL30737799 | 0.95 | SENP1 (0.38) | SENP1CASP1CHEK1DAPK3PRKD3 | |
| SCHEMBL2571796 | 0.95 | SENP1 (0.38) | SENP1CASP1CHEK1DAPK3PRKD3 | |
| SCHEMBL2571801 | 0.95 | SENP1 (0.38) | SENP1CASP1CHEK1DAPK3PRKD3 | |
| SCHEMBL31093978 | 0.93 | RXFP1 (0.42) | SENP1KMT2AMEN1TP53THRB | |
| SCHEMBL2571237 | 0.93 | RXFP1 (0.42) | SENP1KMT2AMEN1TP53THRB | |
| SCHEMBL2571239 | 0.93 | RXFP1 (0.42) | SENP1KMT2AMEN1TP53THRB | |
| SCHEMBL3719902 | 0.93 | RXFP1 (0.42) | SENP1KMT2AMEN1TP53THRB | |
| SCHEMBL26928300 | 0.93 | BACE1 (0.36) | CHEK1DAPK3PRKD3MAP4K4PAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240271-A1 | USE OF VEGFR2 AND FGFR1 INHIBITORS IN THERAPY | FOUNTAIN THERAPEUTICS INC. (US) | 2023-12-14 | — | — | WO | claimed |
| WO-2023240271-A1 | USE OF VEGFR2 AND FGFR1 INHIBITORS IN THERAPY | FOUNTAIN THERAPEUTICS INC. (US) | 2023-12-14 | — | — | WO | disclosed |