Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2571239 | 1.00 | RXFP1 (0.42) | RXFP1SENP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2571237 | 1.00 | RXFP1 (0.42) | RXFP1SENP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31093978 | 1.00 | RXFP1 (0.42) | RXFP1SENP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2567836 | 0.95 | RXFP1 (0.43) | RXFP1SENP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2567839 | 0.95 | RXFP1 (0.43) | RXFP1SENP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31094012 | 0.95 | RXFP1 (0.43) | RXFP1SENP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL436187 | 0.93 | SENP1 (0.37) | RXFP1SENP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30737878 | 0.93 | SENP1 (0.37) | RXFP1SENP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL436186 | 0.93 | SENP1 (0.37) | RXFP1SENP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2569460 | 0.91 | RXFP1 (0.44) | RXFP1SENP1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057397-A1 | TREATMENT OF CANCER | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-24 | — | — | WO | claimed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |
| WO-2007057397-A1 | TREATMENT OF CANCER | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-24 | — | — | WO | disclosed |