Tetrachloroethylene

Tetrachloroethylene

SCHEMBL3073798

ClC(Cl)=C(Cl)Cl.c1ccncc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.64
NAPRT Q6XQN6 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
NOTUM Q6P988 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL4636073 0.93
Pyridine SCHEMBL8733420 0.89 NAPRT (0.69) TSHRNAPRTTDP1NOTUMMEN1
Pyridine SCHEMBL29072605 0.85
Pyridine SCHEMBL28067297 0.84 NAPRT (0.90) TSHRNAPRTTDP1NOTUMMEN1
Pyridine SCHEMBL6532110 0.84
Pyridine SCHEMBL31396433 0.84
Pyridine SCHEMBL936385 0.83 NAPRT (0.60) TSHRNAPRTTDP1MEN1KMT2A
Pyridine SCHEMBL9851406 0.83 NAPRT (0.60) TSHRNAPRTTDP1MEN1KMT2A
Pyridine SCHEMBL6730524 0.83 NAPRT (0.60) TSHRNAPRTTDP1MEN1KMT2A
Pyridine SCHEMBL28910607 0.81 NAPRT (0.82) TSHRNAPRTTDP1NOTUMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100228020-A1 Novel Chlorination Reagent and a Novel Process for Chlorination of Sugars Using Thionyl Chloride V.B Medicare Pvt. Ltd (IN) 2010-09-09 US disclosed
EP-1996601-A2 PROCESS FOR THE PRODUCTION OF A CHLORINATING REAGENT AND ITS USE IN THE PREPARATION OF CHLORINATED SUGARS V.B. MEDICARE PVT. LTD. (IN) 2008-12-03 EP disclosed
WO-2007099557-A2 PROCESS FOR THE PRODUCTION OF A CHLORINATING REAGENT AND ITS USE IN THE PREPARATION OF CHLORINATED SUGARS V. B. MEDICARE PVT. LTD. (IN) 2007-09-07 WO disclosed