Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | PRKX | P51817 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740030 | 0.84 | HCAR2 (0.45) | ALDH1A1MEN1KMT2ATSHRHCAR2 | |
| SCHEMBL19100029 | 0.83 | TSHR (0.57) | ALDH1A1MEN1KMT2ATSHRHCAR2 | |
| SCHEMBL19924464 | 0.80 | MEN1 (0.45) | ALDH1A1MEN1KMT2ATSHRPLK4 | |
| SCHEMBL21607839 | 0.80 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ATSHRNPC1 | |
| SCHEMBL18343704 | 0.78 | BTK (0.43) | ALDH1A1MEN1KMT2ATSHRPLK4 | |
| SCHEMBL5494056 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ATSHRPLK4 | |
| SCHEMBL27412135 | 0.73 | TSHR (0.49) | ALDH1A1MEN1KMT2ATSHRPLK4 | |
| SCHEMBL2408208 | 0.70 | HSP90AA1 (0.34) | ALDH1A1MEN1KMT2ATSHRHCAR2 | |
| SCHEMBL24993700 | 0.70 | — | — | |
| SCHEMBL10562708 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561993-A1 | INHIBITORS OF PLASMA KALLIKREIN | Rezolute, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024025907-A1 | INHIBITORS OF PLASMA KALLIKREIN | REZOLUTE, INC. (US) | 2024-02-01 | — | — | WO | disclosed |