Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19100029 | 0.84 | TSHR (0.57) | HCAR2ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL30739210 | 0.84 | ALDH1A1 (0.45) | HCAR2ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL21607839 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ATSHRNPC1 | |
| SCHEMBL14822490 | 0.79 | HCAR2 (0.43) | HCAR2ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL535662 | 0.76 | ALDH1A1 (0.39) | HCAR2ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL2408208 | 0.75 | HSP90AA1 (0.34) | HCAR2ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL24993700 | 0.71 | — | — | |
| SCHEMBL10562708 | 0.71 | — | — | |
| SCHEMBL28987726 | 0.70 | MEN1 (0.35) | ALDH1A1MEN1KMT2ATSHRL3MBTL1 | |
| SCHEMBL27756274 | 0.69 | KMT2A (0.42) | HCAR2ALDH1A1KMT2AKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002385-A1 | 1-(QUINOLIN-4-YL)-1H-PYRAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-01-11 | — | — | WO | disclosed |