Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 15/20 | 0.39 |
| ▸ | ITK | Q08881 | 5/20 | 0.39 |
| ▸ | BLK | P51451 | 3/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | MET | P08581 | 4/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739427 | 0.90 | BRD4 (0.42) | BRD4EGFRITKBLKBTK | |
| SCHEMBL30739237 | 0.89 | BLK (0.39) | BRD4EGFRITKBLKBTK | |
| SCHEMBL30739145 | 0.85 | TEK (0.37) | EGFRBLKBTKMET | |
| SCHEMBL30739402 | 0.83 | MAP4K4 (0.37) | — | |
| SCHEMBL30739372 | 0.83 | MAP4K4 (0.40) | — | |
| SCHEMBL30739323 | 0.83 | MAP4K4 (0.36) | — | |
| SCHEMBL30739393 | 0.80 | MAP4K4 (0.32) | MET | |
| SCHEMBL30739409 | 0.78 | CYP3A4 (0.42) | EGFRITKBLKBTK | |
| SCHEMBL30739291 | 0.78 | CYP3A4 (0.51) | BRD4EGFRBLKBTKMET | |
| SCHEMBL30739192 | 0.78 | CYP3A4 (0.51) | BRD4EGFRBLKBTKMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |