Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 6/20 | 0.37 |
| ▸ | BLK | P51451 | 4/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | BMX | P51813 | 3/20 | 0.34 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 4/20 | 0.34 |
| ▸ | EGFR | P00533 | 4/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 3/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739237 | 0.86 | BLK (0.39) | BLKMAP4K4BTKJAK3EGFR | |
| SCHEMBL30739376 | 0.85 | BRD4 (0.40) | BLKBTKEGFRMET | |
| SCHEMBL30739427 | 0.83 | BRD4 (0.42) | BLKBTKJAK3EGFRMET | |
| SCHEMBL30739192 | 0.80 | CYP3A4 (0.51) | BLKBTKJAK3EGFRMET | |
| SCHEMBL30739291 | 0.80 | CYP3A4 (0.51) | BLKBTKJAK3EGFRMET | |
| SCHEMBL30739409 | 0.79 | CYP3A4 (0.42) | BLKBTKJAK3EGFRFGFR1 | |
| SCHEMBL30739302 | 0.78 | EGFR (0.41) | TEKBLKEPHB4BTKJAK3 | |
| SCHEMBL30739372 | 0.75 | MAP4K4 (0.40) | MAP4K4 | |
| SCHEMBL30739402 | 0.74 | MAP4K4 (0.37) | MAP4K4 | |
| SCHEMBL30739323 | 0.73 | MAP4K4 (0.36) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |