SCHEMBL30739488

SCHEMBL30739488

O=C(O)c1cccc(Cc2ccc3ccc(O)cc3c2)c1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 4/20 0.52
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
CA9 Q16790 2/20 0.51
CA12 O43570 1/20 0.51
CA6 P23280 1/20 0.51
FOLH1 Q04609 1/20 0.50
PLA2G2A P14555 1/20 0.45
ALOX5 P09917 1/20 0.44
NR4A2 P43354 1/20 0.44
TRPV1 Q8NER1 1/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
CLK1 P49759 1/20 0.44
DYRK1A Q13627 1/20 0.44
DYRK1B Q9Y463 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29179286 1.00 MRGPRX4 (0.52) MRGPRX4CA1CA2CA9CA12
SCHEMBL4701641 0.85 CA1 (0.60) MRGPRX4CA1CA2CA9CA12
SCHEMBL30791058 0.82 FOLH1 (0.70) CA1CA2CA9CA12CA6
SCHEMBL70351 0.82 FOLH1 (0.70) CA1CA2CA9CA12CA6
SCHEMBL1296450 0.79 CA1 (0.63) CA1CA2CA9FOLH1PLA2G2A
SCHEMBL1926951 0.78 FOLH1 (0.66) CA1CA2CA9FOLH1PLA2G2A
Hydrochloric Acid SCHEMBL7136020 0.77 CA1 (0.61) MRGPRX4CA1CA2CA9FOLH1
SCHEMBL10958615 0.77 ALOX5 (0.59) ALOX5MEN1NPC1RAB9AKMT2A
SCHEMBL186904 0.76 MEN1 (0.58) CA1CA2CA9CA12CA6
SCHEMBL29749984 0.76 MEN1 (0.58) CA1CA2CA9CA12CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466731-B 3- [ (7-Hydroxynaphthalene-2-yl) methyl ] benzoic acid and preparation method and application thereof 华中农业大学 2025-02-14 CN claimed
CN-117466731-A 3- [ (7-hydroxynaphthalene-2-yl) methyl ] benzoic acid and preparation method and application thereof 华中农业大学 2024-01-30 CN claimed
CN-117466731-B 3- [ (7-Hydroxynaphthalene-2-yl) methyl ] benzoic acid and preparation method and application thereof 华中农业大学 2025-02-14 CN disclosed
CN-117466731-B 3- [ (7-Hydroxynaphthalene-2-yl) methyl ] benzoic acid and preparation method and application thereof 华中农业大学 2025-02-14 CN disclosed
CN-117466731-B 3- [ (7-Hydroxynaphthalene-2-yl) methyl ] benzoic acid and preparation method and application thereof 华中农业大学 2025-02-14 CN disclosed
CN-117466731-A 3- [ (7-hydroxynaphthalene-2-yl) methyl ] benzoic acid and preparation method and application thereof 华中农业大学 2024-01-30 CN disclosed
CN-117466731-A 3- [ (7-hydroxynaphthalene-2-yl) methyl ] benzoic acid and preparation method and application thereof 华中农业大学 2024-01-30 CN disclosed
CN-117466731-A 3- [ (7-hydroxynaphthalene-2-yl) methyl ] benzoic acid and preparation method and application thereof 华中农业大学 2024-01-30 CN disclosed