Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.54 |
| ▸ | HNF4A | P41235 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1296450 | 0.89 | CA1 (0.63) | CA1CA2CA9FOLH1PLA2G2A | |
| SCHEMBL1926951 | 0.89 | FOLH1 (0.66) | CA1CA2CA9FOLH1PLA2G2A | |
| SCHEMBL30791058 | 0.89 | FOLH1 (0.70) | CA1CA2CA9FOLH1CA12 | |
| SCHEMBL70351 | 0.89 | FOLH1 (0.70) | CA1CA2CA9FOLH1CA12 | |
| Hydrochloric Acid SCHEMBL7136020 | 0.87 | CA1 (0.61) | CA1CA2CA9FOLH1PLA2G2A | |
| SCHEMBL29179286 | 0.85 | MRGPRX4 (0.52) | CA1CA2CA9FOLH1CA12 | |
| SCHEMBL30739488 | 0.85 | MRGPRX4 (0.52) | CA1CA2CA9FOLH1CA12 | |
| SCHEMBL24484775 | 0.84 | SRD5A2 (0.62) | CA1CA2CA9FOLH1PLA2G2A | |
| SCHEMBL6865180 | 0.84 | CA1 (0.62) | CA1CA2CA9FOLH1PLA2G2A | |
| SCHEMBL7945362 | 0.83 | ESR1 (0.56) | CA1CA2CA9CA12CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835812-A | anti-PD-L1 antibodies and their use for enhancing T cell function | 霍夫曼-拉罗奇有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-105246474-B | Life-prolonging composition containing (+) eugenol | 株式会社爱茉莉太平洋 | 2018-06-08 | — | — | CN | disclosed |
| CN-105246474-A | Life-prolonging composition containing (+) eugenol | AMOREPACIFIC CORP | 2016-01-13 | — | — | CN | disclosed |
| CN-102612381-B | Hazardous agent injection system | ANTARES PHARMA INC. (US) | 2015-09-09 | — | — | CN | disclosed |
| CN-104479018-A | Anti-pd-l1 antibodies and their use to enhance t-cell function | HOFFMANN LA ROCHE | 2015-04-01 | — | — | CN | disclosed |
| CN-102245640-B | Anti-PD-L1 antibodies and their use for enhancing T cell function | HOFFMANN LA ROCHE | 2014-12-31 | — | — | CN | disclosed |
| CN-102245640-A | Anti-PD-L1 antibodies and their use for enhancing T cell function | HOFFMANN LA ROCHE | 2011-11-16 | — | — | CN | disclosed |
| EP-1919914-A2 | P38 MAP KINASE INHIBITORS AND METHODS FOR USING THE SAME | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007023115-A2 | P38 MAP KINASE INHIBITORS AND METHODS FOR USING THE SAME | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-01 | — | — | WO | disclosed |
| US-6924284-B2 | PARP inhibitors | ICOS CORPORATION (US) | 2005-08-02 | — | — | US | disclosed |