Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 10/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.39 |
| ▸ | GSK3B | P49841 | 6/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29197875 | 0.87 | MEN1 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Iodide SCHEMBL28993211 | 0.86 | MEN1 (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Bromide SCHEMBL29204390 | 0.86 | MEN1 (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Bromide SCHEMBL27722294 | 0.84 | MEN1 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Iodide SCHEMBL28413314 | 0.78 | GSK3B (0.40) | GSK3B | |
| SCHEMBL29603098 | 0.78 | ALDH1A1 (0.38) | GSK3BMEN1POLBKMT2A | |
| SCHEMBL21803246 | 0.78 | KDM1A (0.39) | GSK3B | |
| SCHEMBL29221349 | 0.76 | MAOA (0.34) | GSK3BMEN1POLBKMT2A | |
| SCHEMBL6313787 | 0.76 | KDM1A (0.43) | GSK3BPOLB | |
| SCHEMBL28399716 | 0.75 | PIM1 (0.45) | MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874638-B | Meso-position substituted pentamethine cyanine dye, preparation method and application thereof, and fluorescent probe | 西安建筑科技大学 | 2024-01-19 | — | — | CN | disclosed |