SCHEMBL30739624

SCHEMBL30739624

NC(=O)[C@H]1[C@H](c2cc(F)cc(C(F)(F)F)c2)C1(Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
FFAR4 Q5NUL3 1/20 0.34
FFAR1 O14842 1/20 0.34
RIPK1 Q13546 1/20 0.34
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
CES2 O00748 1/20 0.32
TACR1 P25103 2/20 0.31
SLC9A1 P19634 1/20 0.31
VNN1 O95497 1/20 0.31
GAA P10253 1/20 0.31
XPO1 O14980 1/20 0.30
KCNN4 O15554 1/20 0.30
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18146668 0.87 FFAR4 (0.39) KMT2AMEN1LMNAFFAR4FFAR1
SCHEMBL23340708 0.87 FFAR4 (0.39) KMT2AMEN1LMNAFFAR4FFAR1
SCHEMBL18146666 0.87 FFAR4 (0.39) KMT2AMEN1LMNAFFAR4FFAR1
SCHEMBL18146663 0.87 FFAR4 (0.39) KMT2AMEN1LMNAFFAR4FFAR1
SCHEMBL30739838 0.86 SLC9A1 (0.42) KMT2AMEN1LMNAFFAR4CES2
SCHEMBL30739738 0.80 CES2 (0.41) LMNACES2SLC9A1MAPT
SCHEMBL29493881 0.77 CES2 (0.40) KMT2AMEN1LMNAFFAR4RXRA
SCHEMBL18144169 0.77 CES2 (0.40) KMT2AMEN1LMNAFFAR4RXRA
SCHEMBL18144165 0.77 CES2 (0.40) KMT2AMEN1LMNAFFAR4RXRA
SCHEMBL29493871 0.77 CES2 (0.40) KMT2AMEN1LMNAFFAR4RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 CN disclosed