SCHEMBL30739657

SCHEMBL30739657

Cc1ccccc1C(=O)Nc1ccc(F)cc1F

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.66
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
KDM4E B2RXH2 1/20 0.56
KLK7 P49862 1/20 0.56
PKM P14618 2/20 0.56
POLB P06746 1/20 0.56
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
TAS1R3 Q7RTX0 1/20 0.55
TAS1R1 Q7RTX1 1/20 0.55
TAS1R2 Q8TE23 1/20 0.55
HTT P42858 3/20 0.54
ALDH1A1 P00352 3/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
HPGD P15428 1/20 0.53
GAA P10253 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12225784 1.00 MAPT (0.66) MAPTMEN1KMT2AKDM4EKLK7
SCHEMBL30739720 0.88 MAPT (0.59) MAPTMEN1KMT2AKDM4EKLK7
SCHEMBL5445708 0.86 ALDH1A1 (0.62) MAPTMEN1KMT2AKDM4EPKM
SCHEMBL30599567 0.86 MAPT (0.71) MAPTMEN1KMT2AKDM4EKLK7
SCHEMBL24170145 0.84 HPGD (0.56) MEN1KMT2AKDM4ENPC1RAB9A
SCHEMBL17772176 0.84 HTT (0.63) MEN1KMT2AKDM4ENPC1RAB9A
SCHEMBL30739829 0.84 MAPT (0.60) MAPTMEN1KMT2AKDM4EKLK7
SCHEMBL4177886 0.83 MAPT (0.68) MAPTMEN1KMT2AKDM4EKLK7
SCHEMBL7821783 0.83 MAPT (0.74) MAPTMEN1KMT2AKDM4EKLK7
SCHEMBL15333340 0.83 KDM4E (0.78) MAPTMEN1KMT2AKDM4EKLK7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 CN disclosed