Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739657 | 0.86 | MAPT (0.66) | ALDH1A1KDM4EPOLBMAPTKMT2A | |
| SCHEMBL12225784 | 0.86 | MAPT (0.66) | ALDH1A1KDM4EPOLBMAPTKMT2A | |
| SCHEMBL5445940 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KDM4EPOLBMAPTKMT2A | |
| SCHEMBL24769824 | 0.81 | EPHX1 (0.57) | ALDH1A1POLBMAPTKMT2AMEN1 | |
| SCHEMBL14825211 | 0.81 | ALDH1A1 (0.73) | ALDH1A1KDM4EPOLBALOX12MAPT | |
| SCHEMBL5456687 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EPOLBALOX12MAPT | |
| SCHEMBL5450444 | 0.78 | GRM1 (0.55) | ALDH1A1KDM4EPOLBMAPTKMT2A | |
| SCHEMBL5447995 | 0.77 | MAPT (0.68) | ALDH1A1KDM4EPOLBALOX12MAPT | |
| SCHEMBL5457277 | 0.76 | ALDH1A1 (0.74) | ALDH1A1KDM4EPOLBALOX12MAPT | |
| SCHEMBL30739720 | 0.76 | MAPT (0.59) | ALDH1A1KDM4EPOLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |