Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 10/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20051344 | 1.00 | P2RX7 (0.38) | P2RX7POLBAPEX1PDCD1LG2CD274 | |
| SCHEMBL30739575 | 0.86 | P2RX7 (0.34) | P2RX7POLBAPEX1PDCD1LG2CD274 | |
| SCHEMBL20050950 | 0.86 | P2RX7 (0.34) | P2RX7POLBAPEX1PDCD1LG2CD274 | |
| SCHEMBL20051270 | 0.81 | GPR35 (0.34) | P2RX7AKR1B1NR3C1 | |
| SCHEMBL20050524 | 0.81 | CNR1 (0.46) | P2RX7AKR1B1 | |
| SCHEMBL30739939 | 0.81 | CNR1 (0.46) | P2RX7AKR1B1 | |
| SCHEMBL20050523 | 0.80 | AKR1B1 (0.37) | P2RX7POLBAPEX1AKR1B1 | |
| SCHEMBL30739651 | 0.80 | AKR1B1 (0.37) | P2RX7POLBAPEX1AKR1B1 | |
| SCHEMBL20051354 | 0.79 | MAPT (0.40) | P2RX7 | |
| SCHEMBL20051338 | 0.79 | P2RX7 (0.51) | P2RX7CFTRNTRK1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118044519-A | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-110072842-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-02-02 | — | — | CN | disclosed |