SCHEMBL30739711

SCHEMBL30739711

NC(=O)C1C(c2ccc(F)c(I)c2)C1(Cl)Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 7/20 0.41
KMT2A Q03164 6/20 0.39
MAPT P10636 2/20 0.39
MEN1 O00255 5/20 0.38
LMNA P02545 3/20 0.38
ALDH1A1 P00352 1/20 0.33
RECQL P46063 1/20 0.33
ABCC9 O60706 1/20 0.33
ABCC8 Q09428 1/20 0.33
KCNJ11 Q14654 1/20 0.33
KCNJ8 Q15842 1/20 0.33
HTT P42858 3/20 0.33
MAPK1 P28482 1/20 0.33
HPGD P15428 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20045651 0.87 MEN1 (0.42) SLC9A1KMT2AMAPTMEN1LMNA
SCHEMBL29241571 0.87 MEN1 (0.42) SLC9A1KMT2AMAPTMEN1LMNA
SCHEMBL30739896 0.84 KMT2A (0.43) SLC9A1KMT2AMAPTMEN1LMNA
SCHEMBL30739760 0.84 KMT2A (0.43) SLC9A1KMT2AMAPTMEN1LMNA
SCHEMBL30739957 0.81 SLC9A1 (0.49) SLC9A1KMT2AMAPTMEN1LMNA
SCHEMBL30739583 0.81 KMT2A (0.45) SLC9A1KMT2AMAPTMEN1LMNA
SCHEMBL30739926 0.81 KMT2A (0.54) SLC9A1KMT2AMAPTMEN1LMNA
SCHEMBL30739761 0.80 SLC9A1 (0.40) SLC9A1KMT2AMAPTMEN1LMNA
SCHEMBL20076634 0.80 SLC9A1 (0.40) SLC9A1KMT2AMAPTMEN1LMNA
SCHEMBL30739948 0.77 KMT2A (0.60) SLC9A1KMT2AMAPTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 CN disclosed