SCHEMBL30739765

SCHEMBL30739765

CC(C)CC(=O)CNC(=O)c1cc(N)ccc1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 3/20 0.49
HSD17B10 Q99714 2/20 0.47
TSHR P16473 1/20 0.47
HTT P42858 1/20 0.47
PSMB8 P28062 2/20 0.46
PSMB9 P28065 2/20 0.46
PSMB6 P28072 2/20 0.46
PSMB5 P28074 2/20 0.46
PSMB10 P40306 2/20 0.46
PSMB11 A5LHX3 1/20 0.46
PSMA7 O14818 1/20 0.46
NFKB1 P19838 1/20 0.46
PSMB1 P20618 1/20 0.46
PSMA1 P25786 1/20 0.46
PSMA2 P25787 1/20 0.46
PSMA3 P25788 1/20 0.46
PSMA4 P25789 1/20 0.46
PDE4A P27815 1/20 0.46
PSMA5 P28066 1/20 0.46
PSMB4 P28070 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20050947 1.00 P2RX7 (0.49) P2RX7HSD17B10TSHRHTTPSMB8
SCHEMBL20050522 0.85 P2RX7 (0.52) P2RX7HSD17B10TSHRHTTPSMB8
SCHEMBL30739837 0.85 P2RX7 (0.52) P2RX7HSD17B10TSHRHTTPSMB8
SCHEMBL30739900 0.81 P2RX7 (0.54) P2RX7HSD17B10TSHRHTTPSMB8
SCHEMBL20051718 0.81 P2RX7 (0.54) P2RX7HSD17B10TSHRHTTPSMB8
SCHEMBL20051723 0.80 KMT2A (0.57) TSHRNFKB1LMNASMN1; SMN2KMT2A
SCHEMBL30739699 0.79 KDM4E (0.36) P2RX7HSD17B10TSHRHTTPSMB8
SCHEMBL20051305 0.79 KDM4E (0.36) P2RX7HSD17B10TSHRHTTPSMB8
SCHEMBL7224774 0.78 P2RX7 (0.57) P2RX7HSD17B10TSHRHTTLMNA
SCHEMBL13663588 0.75 ALOX5 (0.69) P2RX7HSD17B10TSHRHTTPSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 CN disclosed