Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.53 |
| ▸ | IAPP | P10997 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 3/20 | 0.49 |
| ▸ | MMP1 | P03956 | 3/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | MMP9 | P14780 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28055089 | 1.00 | PELI1 (0.53) | PELI1IAPPPTGS1TTRMMP1 | |
| SCHEMBL21986709 | 1.00 | PELI1 (0.53) | PELI1IAPPPTGS1TTRMMP1 | |
| SCHEMBL5579317 | 0.85 | KDM4E (0.51) | PELI1IAPPPTGS1KDM4EHSD17B10 | |
| SCHEMBL21986720 | 0.84 | IAPP (0.73) | IAPPPTGS1TTRMMP1MMP2 | |
| SCHEMBL14472602 | 0.84 | KDM4E (0.70) | IAPPPTGS1TTRMMP1MMP2 | |
| SCHEMBL21986902 | 0.84 | IAPP (0.73) | IAPPPTGS1TTRMMP1MMP2 | |
| SCHEMBL29773361 | 0.83 | KDM4E (0.69) | PELI1IAPPPTGS1TTRMMP1 | |
| SCHEMBL8916399 | 0.83 | KDM4E (0.69) | PELI1IAPPPTGS1TTRMMP1 | |
| SCHEMBL1314851 | 0.83 | KDM4E (0.69) | PELI1IAPPPTGS1TTRMMP1 | |
| SCHEMBL16093012 | 0.81 | IAPP (0.64) | IAPPPTGS1TTRMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117653618-A | Novel benzalacetone derivative and use thereof | 韩药有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-110996930-B | Novel benzalacetone derivative and use thereof | 韩药有限公司 | 2024-02-02 | — | — | CN | disclosed |