Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | TTR | P02766 | 3/20 | 0.61 |
| ▸ | MMP1 | P03956 | 3/20 | 0.61 |
| ▸ | MMP2 | P08253 | 3/20 | 0.61 |
| ▸ | MMP9 | P14780 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | APP | P05067 | 2/20 | 0.61 |
| ▸ | DPP4 | P27487 | 2/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598948 | 0.89 | KDM4E (0.74) | IAPPPTGS1TTRMMP1MMP2 | |
| SCHEMBL2221673 | 0.89 | KDM4E (0.74) | IAPPPTGS1TTRMMP1MMP2 | |
| SCHEMBL16881737 | 0.87 | IAPP (0.69) | IAPPPTGS1TTRMMP1MMP2 | |
| SCHEMBL8349121 | 0.84 | SNCA (0.82) | MAPTTERTSNCA | |
| SCHEMBL15481424 | 0.84 | BACE1 (0.66) | IAPPPTGS1TTRMMP1MMP2 | |
| SCHEMBL21986720 | 0.82 | IAPP (0.73) | IAPPPTGS1TTRMMP1MMP2 | |
| SCHEMBL14472602 | 0.82 | KDM4E (0.70) | IAPPPTGS1TTRMMP1MMP2 | |
| SCHEMBL21986902 | 0.82 | IAPP (0.73) | IAPPPTGS1TTRMMP1MMP2 | |
| SCHEMBL10021657 | 0.82 | CYP2C9 (0.74) | IAPPPTGS1TTRMMP1MMP2 | |
| SCHEMBL13953735 | 0.82 | BACE1 (0.57) | IAPPPTGS1TTRMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9925153-B2 | Therapeutic agents for skin diseases and conditions | STC.UNM (US) | 2018-03-27 | — | — | US | disclosed |
| US-20160287531-A1 | THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS | STC.UNM | 2016-10-06 | — | — | US | disclosed |
| US-8841326-B2 | Therapeutic curcumin derivatives | STC.UNM (US) | 2014-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160287531-A1 | THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS | CUTA, TSLP, ELANE | IAPP 1553/4885PTGS1 1081/4885TTR 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.