Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20296159 | 1.00 | PTGDR2 (0.45) | PTGDR2TMEM97SIGMAR1GRM5S1PR5 | |
| SCHEMBL20293305 | 0.92 | PARP1 (0.40) | PTGDR2TMEM97SIGMAR1GRM5S1PR5 | |
| SCHEMBL30145264 | 0.92 | PARP1 (0.40) | PTGDR2TMEM97SIGMAR1GRM5S1PR5 | |
| SCHEMBL505382 | 0.81 | PPARA (0.50) | PTGDR2TMEM97SIGMAR1GRM5S1PR5 | |
| SCHEMBL17377166 | 0.81 | DHFR (0.49) | PTGDR2TMEM97SIGMAR1GRM5KDR | |
| SCHEMBL504679 | 0.79 | S1PR5 (0.52) | TMEM97SIGMAR1GRM5S1PR5KDR | |
| SCHEMBL504584 | 0.79 | DHFR (0.44) | PTGDR2TMEM97SIGMAR1GRM5S1PR5 | |
| SCHEMBL505215 | 0.78 | GRM5 (0.56) | GRM5S1PR5DHFR | |
| SCHEMBL504656 | 0.78 | DHFR (0.46) | PTGDR2TMEM97SIGMAR1GRM5KDR | |
| SCHEMBL10250503 | 0.78 | DHFR (0.48) | PTGDR2TMEM97SIGMAR1GRM5S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110582493-B | Benzoxazole derivatives as immunomodulators | 因赛特公司 | 2024-03-08 | — | — | CN | disclosed |