Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI2 | P48307 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 7/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17674406 | 0.87 | TFPI2 (0.55) | TFPI2HTR2AHTR2CKDM4EALDH1A1 | |
| SCHEMBL5568842 | 0.85 | TFPI2 (0.52) | TFPI2PARP1HTR2AHTR2CKDM4E | |
| SCHEMBL25937304 | 0.83 | TFPI2 (0.48) | TFPI2PARP1HTR2AHTR2CKDM4E | |
| Hydrochloric Acid SCHEMBL25429491 | 0.81 | TFPI2 (0.47) | TFPI2PARP1HTR2AHTR2CKDM4E | |
| SCHEMBL25818760 | 0.79 | HTR2C (0.52) | TFPI2HTR2AHTR2CKDM4EALDH1A1 | |
| SCHEMBL5785852 | 0.79 | HTR2A (0.44) | PARP1HTR2AHTR2CFABP4OXER1 | |
| SCHEMBL9033370 | 0.79 | OXER1 (0.57) | PARP1HTR2AHTR2CKDM4EOXER1 | |
| SCHEMBL29949827 | 0.79 | ROCK2 (0.52) | PARP1KDM4EALDH1A1HSD17B10NOTUM | |
| SCHEMBL18867950 | 0.78 | TFPI2 (0.47) | TFPI2HTR2AHTR2CKDM4EALDH1A1 | |
| SCHEMBL9789003 | 0.78 | TFPI2 (0.47) | TFPI2HTR2AHTR2CKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229281-A | Di-parallel ring derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-15 | — | — | CN | disclosed |