Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301583 | 0.87 | MAPT (0.40) | KMT2AKDM4ETSHRLMNAALDH1A1 | |
| SCHEMBL43076 | 0.73 | KDM4E (0.53) | KMT2AKDM4EGAATSHRLMNA | |
| SCHEMBL69723 | 0.73 | HSD17B10 (0.44) | KMT2AKDM4EGAAATMTSHR | |
| SCHEMBL28296968 | 0.72 | CA12 (0.42) | KDM4EGAATSHRLMNAALDH1A1 | |
| SCHEMBL189803 | 0.72 | ALDH1A1 (0.46) | KMT2AKDM4EGAAATMTSHR | |
| SCHEMBL30368537 | 0.72 | KDM4E (0.38) | KMT2AKDM4EGAATSHRLMNA | |
| SCHEMBL22068300 | 0.72 | CHRNA4 (0.48) | KDM4EGAATSHRLMNAALDH1A1 | |
| SCHEMBL8217350 | 0.72 | KDM4E (0.38) | KMT2AKDM4ETSHRLMNAALDH1A1 | |
| SCHEMBL31310778 | 0.72 | HSD17B10 (0.43) | KMT2AKDM4EGAAATMTSHR | |
| SCHEMBL2417181 | 0.72 | CHRNB2 (0.41) | KMT2AKDM4EGAATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |