Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | PDE8B | O95263 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29825675 | 0.84 | FAAH (0.39) | LMNAMAPT | |
| SCHEMBL30740832 | 0.81 | PDE7B (0.38) | PDE7BEPHA2KDREPHB4TSHR | |
| SCHEMBL30740782 | 0.80 | KDM1A (0.41) | PDE7BTSHRLMNAMEN1KMT2A | |
| SCHEMBL30740715 | 0.75 | KMT2A (0.52) | TSHRLMNAMEN1MAPTHTT | |
| SCHEMBL30745371 | 0.73 | ALDH1A1 (0.38) | TSHRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL29826297 | 0.71 | KMT2A (0.43) | TSHRLMNAMEN1MAPTHTT | |
| SCHEMBL24792585 | 0.69 | KMT2A (0.42) | TSHRMEN1HTTKMT2AALDH1A1 | |
| SCHEMBL21714122 | 0.69 | KDM1A (0.42) | PDE7BALDH1A1KDM1APRMT5PDE8B | |
| SCHEMBL30056362 | 0.69 | KMT2A (0.42) | TSHRMEN1HTTKMT2AALDH1A1 | |
| SCHEMBL30740753 | 0.68 | KDM1A (0.46) | TSHRLMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |