SCHEMBL30740752

SCHEMBL30740752

Cc1ccc(C(C)c2ccccc2C(=O)O)c(Cl)c1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.44
ALDH1A1 P00352 1/20 0.44
FTO Q9C0B1 2/20 0.43
POLB P06746 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
AKR1C3 P42330 1/20 0.41
FABP3 P05413 1/20 0.41
FABP4 P15090 1/20 0.41
CSNK2A1 P68400 1/20 0.41
AKR1C2 P52895 1/20 0.40
AKR1C1 Q04828 1/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
NPC1 O15118 1/20 0.40
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2504810 0.81 PTPRG (0.43) RAB9AALDH1A1MEN1KMT2AAKR1C2
SCHEMBL2497978 0.81 ALDH1A1 (0.41) RAB9AALDH1A1POLBMEN1KMT2A
SCHEMBL2497979 0.81 ALDH1A1 (0.41) RAB9AALDH1A1POLBMEN1KMT2A
SCHEMBL2504808 0.81 PTPRG (0.43) RAB9AALDH1A1MEN1KMT2AAKR1C2
SCHEMBL2502168 0.80 HTT (0.42) ALDH1A1AKR1C2AKR1C1
SCHEMBL2502171 0.80 HTT (0.42) ALDH1A1AKR1C2AKR1C1
SCHEMBL134091 0.80 ALDH1A1 (0.59) ALDH1A1POLBKMT2AAKR1C3KDM4E
SCHEMBL29519227 0.80 LMNA (0.45) RAB9ALMNA
SCHEMBL673182 0.80 LMNA (0.45) RAB9ALMNA
SCHEMBL2502620 0.77 ALDH1A1 (0.37) ALDH1A1POLBMEN1KMT2AAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117043154-A GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof 卡莫特医疗有限公司 2023-11-10 CN disclosed