Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 12/20 | 0.46 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27189048 | 0.77 | SRPK1 (0.43) | STAT3SRPK1 | |
| SCHEMBL27189115 | 0.75 | BRAF (0.43) | STAT3SRPK1CYP2C9CYP2C19SLC6A5 | |
| SCHEMBL27189044 | 0.75 | BRAF (0.41) | STAT3SRPK1CYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL30106378 | 0.75 | SRPK1 (0.43) | STAT3SRPK1CYP2C9CYP2C19SLC6A5 | |
| SCHEMBL29158669 | 0.75 | CHRNB2 (0.54) | — | |
| SCHEMBL30740877 | 0.75 | HDAC1 (0.53) | SCN10ASIGMAR1 | |
| SCHEMBL30740974 | 0.73 | SIGMAR1 (0.43) | STAT3SRPK1LDHASLC6A5SLC6A7 | |
| SCHEMBL30106319 | 0.72 | BRAF (0.40) | STAT3SRPK1CYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL27189056 | 0.72 | BRAF (0.41) | STAT3SRPK1CYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL27189058 | 0.72 | SRPK1 (0.43) | STAT3SRPK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | claimed |
| EP-4349818-A1 | NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASE | Azcuris Co., Ltd. (KR) | 2024-04-10 | — | — | EP | disclosed |
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |