Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | STK10 | O94804 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 4/20 | 0.41 |
| ▸ | JAK3 | P52333 | 4/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740949 | 0.88 | JAK2 (0.49) | ALDH1A1KDM4EGSK3BJAK2JAK3 | |
| SCHEMBL30741053 | 0.85 | JAK2 (0.47) | ALDH1A1KDM4EJAK2JAK3CSNK1D | |
| SCHEMBL30741058 | 0.80 | KDM4E (0.45) | ALDH1A1KDM4EJAK2JAK3HPGD | |
| SCHEMBL30741037 | 0.78 | KDM4E (0.43) | ALDH1A1KDM4EHPGDMEN1MAPT | |
| SCHEMBL30741000 | 0.77 | JAK2 (0.47) | ALDH1A1KDM4EJAK2JAK3HPGD | |
| SCHEMBL2658905 | 0.76 | KDM4E (0.55) | ALDH1A1KDM4EJAK2JAK3CSNK1D | |
| SCHEMBL10982170 | 0.76 | MDM2 (0.54) | ALDH1A1KDM4EJAK2JAK3HPGD | |
| SCHEMBL30741086 | 0.75 | KDM4E (0.43) | ALDH1A1KDM4EJAK2JAK3HPGD | |
| SCHEMBL30740997 | 0.74 | KDM4E (0.48) | ALDH1A1KDM4EJAK2JAK3HPGD | |
| SCHEMBL30741107 | 0.72 | JAK2 (0.48) | ALDH1A1KDM4EJAK2JAK3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |