Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | DDX3X | O00571 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740932 | 0.88 | ALDH1A1 (0.48) | JAK2JAK3SMN1; SMN2MAPTNPC1 | |
| SCHEMBL30741037 | 0.84 | KDM4E (0.43) | GAASMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL30741107 | 0.83 | JAK2 (0.48) | JAK2JAK3GAAPOLBHTT | |
| SCHEMBL10982170 | 0.78 | MDM2 (0.54) | JAK2JAK3GAAMAPK10SMN1; SMN2 | |
| SCHEMBL5830691 | 0.76 | JAK2 (0.53) | JAK2JAK3GAAPOLBHTT | |
| SCHEMBL2658889 | 0.75 | JAK2 (0.54) | JAK2JAK3GAAPOLBHTT | |
| SCHEMBL30741086 | 0.75 | KDM4E (0.43) | JAK2JAK3GAAPOLBHTT | |
| SCHEMBL29169669 | 0.74 | HTT (0.49) | JAK2JAK3GAAPOLBHTT | |
| SCHEMBL30741058 | 0.74 | KDM4E (0.45) | JAK2JAK3GAAPOLBHTT | |
| SCHEMBL5647424 | 0.73 | MAPK14 (0.55) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |