Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.45 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30741076 | 0.87 | POLB (0.55) | MCHR1ALDH1A1TRPV1 | |
| SCHEMBL18474172 | 0.82 | MCHR1 (0.61) | HDAC4HDAC1HDAC6MRGPRX4MCHR1 | |
| SCHEMBL21552087 | 0.75 | MCHR1 (0.54) | HDAC4HDAC1HDAC6MRGPRX4MCHR1 | |
| SCHEMBL30740974 | 0.74 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL29158960 | 0.74 | ALDH1A1 (0.45) | HDAC4HDAC1HDAC6MRGPRX4MCHR1 | |
| SCHEMBL2859647 | 0.74 | ALDH1A1 (0.72) | HDAC1MRGPRX4ALDH1A1KDM4ENPC1 | |
| SCHEMBL29551706 | 0.72 | MAPT (0.47) | MRGPRX4ALDH1A1KDM4E | |
| SCHEMBL30046741 | 0.72 | ALDH1A1 (0.73) | HDAC4HDAC1HDAC6SETD7ALDH1A1 | |
| SCHEMBL21551834 | 0.71 | HDAC4 (0.50) | HDAC4HDAC1HDAC6MRGPRX4MCHR1 | |
| SCHEMBL20205517 | 0.71 | SMN1; SMN2 (0.48) | HDAC4HDAC1HDAC6MRGPRX4MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |