Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 2/20 | 0.63 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.53 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30741049 | 0.85 | PDE3B (0.55) | GCGRPDE3BPDE3AJAK2JAK3 | |
| SCHEMBL30741032 | 0.84 | ALDH1A1 (0.56) | GCGRPDE3BPDE3AALDH1A1HPGD | |
| SCHEMBL30741005 | 0.84 | GCGR (0.58) | GCGRPDE3BPDE3AALDH1A1HPGD | |
| SCHEMBL4181389 | 0.84 | GCGR (0.64) | GCGRPDE3BPDE3AJAK2ALDH1A1 | |
| SCHEMBL30741028 | 0.83 | CDC7 (0.50) | GCGRPDE3BPDE3AALOX5PTGES | |
| SCHEMBL29159037 | 0.83 | GCGR (0.57) | GCGRPDE3BPDE3AJAK2JAK3 | |
| SCHEMBL30740975 | 0.82 | GCGR (0.56) | GCGRPDE3BPDE3AALOX5PTGES | |
| SCHEMBL30741073 | 0.81 | PDE3B (0.56) | GCGRPDE3BPDE3AJAK2JAK3 | |
| SCHEMBL4183471 | 0.81 | GCGR (0.78) | GCGRPDE3BPDE3A | |
| SCHEMBL30741059 | 0.81 | NUDT1 (0.48) | GCGRJAK2ALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |